Description
Application Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins. Has been shown to increase the resolution of proteins in 2D gels.

Properties
assay ≥98% （GC）
mol wt micellar avg mol wt 25,000
aggregation number 84
CMC 20-25 mM（20-25°C）
EQP level Premium
transition temp cloud point >100 °C
storage temp. −20°C

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 3

References
reference G.W. Stubbs, Nonionic detergent with no absorbance at 228 μm, best suited for the solubilisation and isolation of membrane proteins. Biochim. Biophys. Acta 426, 46, （1976）
  Lopez, M.F., Proteome analysis. I. Gene products are where the biological action is. J. Chromatogr. 722, 191-202, （1999）
  Aveldano, M.I., et al., Solubilization of myelin membranes by detergents. J. Neurochem. 57, 250-257, （1991）
  Dainese Hatt, P.,, Concentration of, and SDS removal from proteins isolated from multiple two-dimensional electrophoresis gels. Eur. J. Biochem. 246, 336-343, （1997）
  Gould, R.J., et al., Effects of octyl beta-glucoside on insulin binding to solubilized membrane receptors. Biochemistry 20, 6776, （1981）
  Holloway, P.J. and Arundel, P.H., High-resolution two-dimensional electrophoresis of plant proteins. Anal. Biochem. 172, 8-15, （1988）
  Biochemistry 17, 215, （1978）
  J.S. Lazo, D.E. Quinn Anal. Biochem. 102, 68, （1980）
  S. Han, M.L. Tanzer J. Biol. Chem. 254, 10438, （1979）
  W.J. Schneider J. Biol. Chem. 255, 11442, （1980）
  G. Halldén J. Immunol. Methods 124, 103, （1989）
  B. Lorber, L.J. DeLucas, Changes in physico-chemical properties during membrane protein crystallization using a salt as precipitant. J. Cryst. Growth 110, 103, （1991）
Beilstein Beil. 17,V,7,38

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