详情介绍
Description
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Biochem/physiol Actions Two-chain polypeptide hormone produced by the β-cells of pancreatic islets. Its molecular weight is ~5800 Da. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat.
Properties
form powder
cation traces Zn: ~0.5%
storage temp. −20°C
Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements 22-24/25
WGK Germany 3
References
reference Smith, L.F., Species variation in the amino acid sequence of insulin. Am. J. Med. 40, 662-666, (1966)
Kono, T., Insulin-sensitive glucose transport. Vitam. Horm. 7, 103-154, (1988)
Merck Merck 13,5003
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