Description
Biochem/physiol Actions Mode of Action: Inhibits elongation at transpeptidation step.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes Macrolide antibiotic.
  Inhibits bacterial protein synthesis by binding to the ribosomes1; Inducible erythromycin resistance in bacteria2

Properties
assay ≥90.0% （NT）
optical activity [α]20/D −75±4°, c = 2% in ethanol
mp 133-135 °C
Gene Information human ... ABCB1（5243）, CYP3A4（1576）, MLNR（2862）
  mouse ... Abcb1a（18671）, Abcb1b（18669）

Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 2
RTECS KF4375000

References
Cited Reference 1. H. Teraoka Umsch. Wiss. Tech 77, 347, （1977）
  2. B. Weisblum Br. Med. Bull. 40, 47, （1984） Abstract
Merck Merck 13,3714
Beilstein Beil. 18,V,10,398

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