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阿糖胞苷/胞嘧啶-β-D-呋喃阿拉伯糖苷/1-β-D-阿拉伯呋喃糖基-4-氨基-2(1H)-嘧啶酮/
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型号:Z0121

更新时间:2017-07-14  |  阅读:1282

详情介绍

 Description
Biochem/physiol Actions Ara-C incorporates into DNA and inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation; does not inhibit RNA synthesis. Anti-leukemia agent.

Properties
assay ≥99.0% (HPLC)
optical activity [α]20/D +158±2°, c = 1% in H2O
solubility H2O: 50 mg/mL, clear, colorless
Gene Information human ... POLB(5423)
  mouse ... Cda(72269)

Safety
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes Xn
Risk Statements 43-63
Safety Statements 36/37
WGK Germany 3
RTECS HA5425000

References
Merck Merck 13,2813
Beilstein Beil. 25,IV,3669

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