详情介绍
Description
Biochem/physiol Actions Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Properties
assay ≥97%
bp 150 °C/5 mmHg(lit.)
mp 28-30(lit.)
Gene Information human ... GRIN2B(2904)
rat ... Grin2a(24409)
storage temp. 2-8°C
中文同义词: 精胺;O,O-二甲基硫代磷酰胺;O,O-二甲基硫代磷酰胺(精胺 )
英文名称: O,O-Dimethyl phosphoramidothioate
英文同义词: O,O-Dimethyl thiophosphoramidate;o,o-dimethyl phosphoramidothioate;O,O-Dimethyl Phosphoroamido Thioate;O,O-dimethylamidothiophosphate;O,O-DimethylPhosphoramidothionate;O,O-DIMETHYL THIOPHORAMIDOTHIONATE;E-118 amide;SPERMINE(RG)
CAS号: 17321-47-0
分子式: C2H8NO2PS
分子量: 141.13
化学性质 本品为无色液体,b.p.72~73℃/160 Pa,n20D 1.5025,不溶于水。
用途 O,O-二甲基硫代磷酰胺简称精胺或精酰胺,是合成甲胺磷的中间体。
用途 主要用作甲胺磷、乙酰甲胺磷的中间体