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N-乙基顺丁烯二酰亚胺/1-乙基-1H-吡咯-2,5-二酮/N-乙基失水苹果酰亚胺/N-乙基马来酰亚
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型号:Q0060

更新时间:2017-08-03  |  阅读:1102

详情介绍

 Description
Application Reagent for the covalent modification of cysteine residues in proteins.
Biochem/physiol Actions Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
  Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
Preparation Note NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and significantly dependent on pH. 

Properties
assay ≥98% (HPLC)
form crystalline
bp 210 °C(lit.)
mp 43-46 °C(lit.)
Gene Information human ... KCNQ2(3785), KCNQ4(9132), KCNQ5(56479), SLC6A3(6531), SLC6A4(6532)
storage temp. 2-8°C

中文名称: N-乙基马来酰亚胺
中文同义词: 1-乙基-1H-吡咯-2,5-二酮;N-乙基马来酰亚胺;N-乙基失水苹果酰亚胺;N-乙基顺丁烯二酰亚胺;N-乙基顺丁烯二酰亚胺(NEM);N-乙基马来酰亚胺, 99+%;N-乙基马来酰亚胺, 98+%
英文名称: N-Ethylmaleimide
英文同义词: 1-ethyl-1h-pyrrole-5-dione;5-dione,1-ethyl-1H-Pyrrole-2;ethvlmaleimide;Ethylmaleimide;Maleic acid N-ethylimide;maleicacidn-ethylimide;Maleimide, N-ethyl-;n-ethvlmaleimide
CAS号: 128-53-0
分子式: C6H7NO2
分子量: 125.13
 

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