详情介绍
Description
Application Used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
Biochem/physiol Actions An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when it was combined with copper concentrations at 5 μM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Reconstitution Prepare a 0.1M solution in glycerol:PBS (9:1)
Properties
assay ≥98.5%
form powder
mp 146-149 °C(lit.)
solubility ethanol: soluble50 mg/mL
中文名称: 没食子酸丙酯
中文同义词: 3,4,5-三羟基苯甲酸丙酯;没食子酸丙酯;3,4,5-三羟基苯甲酸正丙酯;倍酸丙酯;丙基-3,4,5-三羟基苯甲酸酯;五倍子酸丙酯;雷尼替丁杂质B;棓丙酯
英文名称: Propyl gallate
英文同义词: 3,4,5-TRIHYDROXYBENZENE-1-PROPYLCARBOXYLATE;3,4,5-TRIHYDROXYBENZOIC ACID N-PROPYL ESTER;3,4,5-TRIHYDROXYBENZOIC ACID PROPYL ESTER;GALLIC ACID N-PROPYL ESTER;GALLIC ACID PROPYL ESTER;FEMA 2947;FEMA 2974;PROGALLIN P
CAS号: 121-79-9
分子式: C10H12O5
分子量: 212.2
化学性质 乳白色针状结晶或白色至淡黄褐色结晶性粉末,无臭,稍有苦味,熔点150℃。对热较稳定,遇光有利于分解,遇铜、铁离子呈紫色或暗绿色,有吸湿性。易溶于热水、乙醇、丙二醇、甘油、棉子油、猪油、花生油和乙醚,难溶于冷水。0.25%的水溶液PH约为5.5。大白鼠经口LD503800mg/kg,ADI 0-1.4mg/kg(FAO/WHO,1994)。
Q0242 没食子酸甲酯/棓酸甲酯/五棓子酸甲酯/3,4,5-三羟基苯甲酸甲酯/Methyl gallate CP,98% 100克 Kayon
Q0243 没食子酸正丙酯/没食子酸丙酯/3,4,5-三羟基苯甲酸丙酯/五子酸丙酯/Propyl gallate CP,98.5% 100克 Kayon
Q0249 乙酸铵/乙酸铔/醋酸铵/Ammonium acetate AR,98% 500克 Kayon
Q0250 结晶乙酸钠/三水合乙酸钠/结晶醋酸钠/乙酸钠结晶/三水醋酸钠/Sodium acetate trihydrate AR,99% 500克 Kayon
Q0252 二乙三胺五乙酸/二乙三胺五醋酸/二亚乙基三胺五乙酸/二乙烯三胺五乙酸/二乙烯三胺五醋酸/ DETAPAC/DTPA AR,99% 100克 Kayon
Q0253 羟基乙酸/甘醇酸/羟基醋酸/乙醇酸/Glycolic acid CP,98% 25克 Kayon
Q0253-1 羟基乙酸钠/羟基乙酸单钠盐/乙醇酸钠/甘醇酸钠/羟基醋酸钠/Sodium glycollate CP,97% 25克 Kayon
Q0254 5-羟基吲哚乙酸/5-羟吲哚乙酸/5-羟基吲哚-3-乙酸/5-HIAA 98% 100毫克 Kayon
250毫克 Kayon
Q0255 4-甲氧基苯乙酸/对甲氧基苯乙酸/4-Methoxyphenylacetic acid 99% 100克 Kayon
500克 Kayon
Q0257 三乙烯四胺六乙酸/三亚乙基四胺六乙酸-3,6,9,12-四羧甲基-3,6,9,12-四氮杂十四烷二羧酸/TTHA 特纯,98% 2克 Kayon
10克 Kayon
Q0258 扁桃酸/苦杏仁酸/杏仁酸/α-羟基苯乙酸/苯基羟乙酸/苯基乙醇酸/苯羟乙酸/2-羟基-2-苯基乙酸/苯乙醇酸/DL-扁桃酸/DL-苦杏仁酸/Mandelic acid AR,99% 25克 Kayon
Q0260 11-氨基十一烷酸/ω-氨基十一烷酸/11-氨基十一酸/11-Aminoundecanoic acid AR,99% 5克 Kayon
100克 Kayon
Q0261 二十二烷酸/山芋酸/二十二碳酸/山嵛酸/扁油酸/萮树酸/山萮酸/二十二酸/Behenic acid AR,85% 100克 Kayon
500克 Kayon